Medical-Grade Diazepam Powder (≥99% Purity) – Research Use Only

• Product Name: Diazepam (Medical Grade)Medical-Grade

• IUPAC Name: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one

• CAS Number: 439-14-5

• Synonyms / Trade Names: Valium, NSC 77518, Ro 5-2807, Vazepam

• Molecular Formula: C₁₆H₁₃ClN₂O

• Molecular Weight: 284.74 g/mol

• Chemical Class: Benzodiazepine

• Form: Fine crystalline powder

• Purity: ≥99% (High-purity, medical-grade for analytical/research purposes)

• Appearance: White to off-white crystalline powder

• Grade: USP/EP-compliant – Research Use Only

• Available Pack Sizes: 10 g | 25 g | 50 g | 100 g | Bulk quantities upon request

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Pharmacological Profile

Mechanism of Action:
Diazepam acts as a positive allosteric modulator of the gamma-aminobutyric acid type A (GABA-A) receptor. It enhances GABAergic inhibition throughout the CNS, leading to anxiolytic, anticonvulsant, muscle relaxant, and sedative effects.

Applications in Research:

• Neuropharmacology studies

• Seizure models (epileptiform activity)

• Substance dependence/addiction withdrawal modeling

  Because of its relatively long duration of action, and evidence of safety and efficacy, diazepam is preferred over other benzodiazepines for the treatment of persons experiencing moderate to severe alcohol withdrawal.^[45] An exception to this is when a medication is required intramuscular in which case either lorazepam or midazolam is recommended.^[45]

• Muscle relaxation and motor control investigations

• Behavioral and psychological research (e.g., anxiety, fear response)

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Storage & Stability

• Storage Conditions: Store in a cool, dry place at 2–8°C. Protect from light and moisture.

• Shelf Life: 24 months from the date of manufacture when stored under recommended conditions.

• Stability: Chemically stable under recommended storage. Avoid exposure to heat, humidity, and direct sunlight.

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Safety & Handling

Hazard Classification (GHS):

• H302: Harmful if swallowed

• H315: Causes skin irritation

• H319: Causes serious eye irritation

• H335: May cause respiratory irritation

Precautions:

• For laboratory research use only. Not for diagnostic or therapeutic use in humans or animals.

• Use personal protective equipment (PPE) including gloves, lab coat, and eye protection.

• Work in a well-ventilated area or under a certified chemical fume hood.

First Aid Measures:

• Inhalation: Move to fresh air. Seek medical attention if symptoms persist.

• Ingestion: Do not induce vomiting. Rinse mouth. Seek immediate medical help.

• Skin Contact: Wash with soap and water. Remove contaminated clothing.

• Eye Contact: Rinse cautiously with water for several minutes. Seek medical advice if irritation persists.

Disposal:
Dispose of waste material in accordance with local, regional, and national regulations.

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Regulatory & Compliance

• Control Status: Regulated substance in many jurisdictions. Buyer must ensure proper licenses and compliance.

• Intended Use: Scientific research, analytical development, pharmaceutical reference testing

• Documentation: Certificate of Analysis (COA), Safety Data Sheet (SDS), and analytical traceability available upon request.

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Ordering Information

Lead Time: 2–5 business days (depending on regulatory clearance and destination country)

Shipping Conditions: Shipped in tamper-evident, insulated containers with temperature control (if required).